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Inactivated
Influenza Vaccine 2005-2006
What You Need
To Know
1. Why get vaccinated?
Influenza (“flu”) is a very contagious disease.
It is caused by the influenza virus, which spreads
from infected persons to the nose or throat of others.
Other illnesses can have the same symptoms and are
often mistaken for influenza. But only an illness caused by the
influenza virus is really influenza.
Anyone can get influenza. For most people, it lasts
only a few days. It can cause: fever · sore throat · chills ·
fatigue· cough · headache · muscle aches
Some people get much sicker. Influenza can lead to
pneumonia and can be dangerous for people with heart or breathing
conditions. It can cause high fever and seizures in children.
Influenza kills about 36,000 people each year in the United States,
mostly among the elderly.
Influenza vaccine can prevent influenza.
2. Influenza
Vaccine
There are two types of influenza vaccine:
An inactivated (killed) vaccine, given as a
shot, has been used in the United States for many years.
A live, weakened vaccine was licensed in
2003. It is sprayed into the nostrils.
This vaccine is described in a
separate Vaccine Information Statement.
Influenza viruses are constantly changing.
Therefore, influenza vaccines are updated every year, and an annual
vaccination is recommended.
For most people influenza vaccine prevents serious
illness caused by the influenza virus. It will not prevent
“influenza-like” illnesses caused by other viruses.
It takes about 2 weeks for protection to develop
after the shot, and protection can last up to a year.
Inactivated influenza vaccine may be given at the
same time as other vaccines, including pneumococcal vaccine.
Some inactivated influenza vaccine contains
thimerosal, a preservative that contains mercury. Some people
believe thimerosal may be related to developmental problems in
children. In 2004 the Institute of Medicine published a report
concluding that, based on scientific studies, there is no evidence
of such a relationship. If you are concerned about thimerosal, ask
your doctor about thimerosal-free influenza vaccine.
3. Who should get inactivated
influenza vaccine?
Influenza vaccine can be given to people 6 months of
age and older. It is recommended for people who are at risk of
serious influenza or its complications, and for people who
can spread influenza to those at high risk (including all
household members):
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People at high risk for complications from
influenza:
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All children 6-23 months of age.
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People 65 years of age and older.
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Residents of long-term care facilities
housing persons with chronic medical conditions.
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People who have long-term health problems
with:
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heart disease
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kidney disease
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lung disease
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metabolic disease, such as diabetes
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asthma
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anemia, and other blood disorders
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People with certain conditions (such as
neuromuscular disorders) that can cause breathing problems.
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People with a weakened immune system due
to:
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HIV/AIDS or other diseases affecting the immune
system
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long-term treatment with drugs such as steroids
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cancer treatment with x-rays or drugs
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People 6 months to 18 years of age on long-term
aspirin treatment (these people could develop Reye Syndrome if
they got influenza).
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Women who will be pregnant during influenza
season.
People who can spread influenza to those at high
risk:
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Household contacts and out-of-home caretakers
of infants from 0-23 months of age.
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Physicians, nurses, family members, or anyone else
in close contact with people at risk of serious influenza.
Influenza vaccine is also recommended for adults
50-64 years of age and anyone else who wants to reduce their
chance of catching influenza.
An annual flu shot should be considered for:
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People who provide essential community services.
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People living in dormitories or under other
crowded conditions, to prevent outbreaks.
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People at high risk of influenza complications who
travel to the Southern hemisphere between April and
September, or to the tropics or in organized tourist groups at any
time.
4. When should I
get influenza vaccine?
The best time to get influenza vaccine is in
October or November.
Influenza season usually peaks in February, but it
can peak any time from November through May. So getting the vaccine
in December, or even later, can be beneficial in most years.
Some people should get their flu shot in October
or earlier:
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people 50 years of age and older,
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younger people at high risk from influenza
and its complications (including children 6 through 23 months
of age),
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household contacts of people at high risk,
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healthcare workers, and
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children younger than 9 years of age
getting influenza vaccine for the first time.
Most people need one flu shot each year. Children
younger than 9 years of age getting influenza vaccine for the first
time should get 2 doses, given at least one month apart.
5. Some people should talk with a doctor before
getting influenza vaccine
Some people should not get inactivated influenza
vaccine or should wait before getting it.
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Tell your doctor if you have any severe
(life-threatening) allergies. Allergic reactions to influenza
vaccine are rare.
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Influenza vaccine virus is grown in eggs. People
with a severe egg allergy should not get the vaccine.
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A severe allergy to any vaccine component is
also a reason to not get the vaccine.
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If you have had a severe reaction after a
previous dose of influenza vaccine, tell your doctor.
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Tell your doctor if you ever had Guillain-Barré
Syndrome (a severe paralytic illness, also called GBS). You may be
able to get the vaccine, but your doctor should help you make the
decision.
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People who are moderately or severely ill should
usually wait until they recover before getting flu vaccine. If you
are ill, talk to your doctor or nurse about whether to reschedule
the vaccination. People with a mild illness can usually get the
vaccine.
6. What are the
risks from inactivated influenza vaccine?
A vaccine, like any medicine, could possibly cause
serious problems, such as severe allergic reactions. The risk of a
vaccine causing serious harm, or death, is extremely small.
Serious problems from influenza vaccine are very
rare. The viruses in inactivated influenza vaccine have been
killed, so you cannot get influenza from the vaccine.
Mild problems:
If these problems occur, they usually begin soon
after the shot and last 1-2 days.
Severe problems:
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Life-threatening allergic reactions from vaccines
are very rare. If they do occur, it is within a few minutes to a
few hours after the shot.
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In 1976, a certain type of influenza (swine flu)
vaccine was associated with Guillain-Barré Syndrome (GBS). Since
then, flu vaccines have not been clearly linked to GBS. However,
if there is a risk of GBS from current flu vaccines, it would be
no more than 1 or 2 cases per million people vaccinated. This is
much lower than the risk of severe influenza, which can be
prevented by vaccination.
7. What if there is a severe reaction?
What should I look for?
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Any unusual condition, such as a high fever or
behavior changes. Signs of a serious allergic reaction can include
difficulty breathing, hoarseness or wheezing, hives, paleness,
weakness, a fast heart beat or dizziness.
What should I do?
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Call a doctor, or get the person to a doctor right
away.
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Tell your doctor what happened, the date and time
it happened, and when the vaccination was given.
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Ask your doctor, nurse, or health department to
report the reaction by filing a Vaccine Adverse Event Reporting
System (VAERS) form.
Or you can file this report through the VAERS web
site at www.vaers.hhs.gov, or by calling 1-800-822-7967.
VAERS does not provide medical advice.
8. The National Vaccine Injury Compensation Program
In the event that you or your child has a serious
reaction to a vaccine, a federal program has been created to help
pay for the care of those who have been harmed.
For details about the National Vaccine Injury
Compensation Program, call 1-800-338-2382 or visit their website at
www.hrsa.gov/osp/vicp
9. How can I learn more?
Ask your immunization provider. They can give you
the vaccine package insert or suggest other sources of information.
Department of Health and Human services
Centers for Disease Control and Prevention
National Immunization Program
Inactivated Influenza Vaccine (7/18/05) Vaccine
Information Statement
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